Isotopic Labeling of Biotherapeutics
HORIZON EUROPE - MSCA - DN - 2021 #101072780 01-02-2023 to 31-01-2027
RESEARCH ARTICLES
DC8 Anika Schick
"High-throughput hydrogen isotope exchange via transfer deuteration"
Schick, A., Bauer, C., Slagbrand, T., Guerzoni, M., Johansson, M., Ghalawat, S., Johansson, M., Norrby, P.-O., Elmore, C.S., and Artelsmair, M.
Organic Chemistry Frontiers, 2026. DOI: 10.1039/D6QO000301J
"Palladacarboxamide Capping Reagents for Carbon Isotope Labeling and Pharmaceutical Diversification"
Hoffmann, D.V., Schick, A., Kjær, L., Enemærke, V.J., Kaussler, C., Torp, J., Martínez-Pardo, P., Elmore, C.S., Skrydstrup, T.
Angew. Chem. Int. Ed., 2026, e1188892 DOI: 10.1002/anie.1188892
DC9 Elisa Martinelli
"Radiolabeling of oligopeptides by selective hydrogen isotope exchange with deuterium and tritium in aqueous buffers"
Martinelli, E., Weck, R., Güssregen, S., Derdau, V.
Nature Communications, 2026, 17, 2317.DOI: 10.1038/s41467-026-69850-x
https://www.nature.com/articles/s41467-026-69850-x
"Pegylated Phosphine Ligands in Iridium(I) Catalyzed Hydrogen Isotope Exchange Reactions in Aqueous Buffers"Martinelli, E, Spiller, M, Weck, R, Llompart, P, Minoletti, C, Güssregen, S, Sib, A, Derdau, V*Chemistry – A European Journal 2024, 30 (48)DOI10.1002/chem.202402038
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202402038
"Site-selective Photoredox-Catalyzed Late-stage Benzylic Hydrogen Isotope Exchange"Stinglhamer, M, Kuhlmann, JH, Martinelli, E, Perulli, S, Sandvoss, M, Mück-Lichtenfeld, C, Derdau, V, Mancheño, OG*Angewandte Chemie – International Edition 2024, 63 (50)DOI10.1002/anie.202411567
https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202411567
REVIEW ARTICLES
DC3 Alfonso Fumanal Idocin
"Sydnonimines: Synthesis, Properties and Applications in Chemical Biology"
Fumanal Idocin, A., Specklin, S., Taran, F.*
Chemical Communications – International Edition, 2025, 61 (XX)
DOI: 10.1039/D5CC00535C
https://pubs.rsc.org/en/content/articlepdf/2025/CC/D5CC00535C?page=search
PRE-PRINTS
DC5 Davide Guglielminotti
''Increasing TET expression and 5-hydroxymethylcytosine formation by a carbocyclic 5-aza-2’-deoxy-cytidine antimetabolite"
Maike Däther, Elsa Peev, Annika Fröhlich, Binje Vick, Sogol Fatourechi, Gilles Gasparoni, Matthias Heiss, Corinna C. Pleintinger, Emmanuel Asu Bisong, Hans Hurmiz, Davide Guglielminotti, Yasmin V. Gärtner, Tina Aumer, Karsten Spiekermann, Jörn Walter, Irmela Jeremias, Franziska R. Traube, Thomas Carell
BOOK CHAPTER
DC1 Rafael Jiménez Rioboo & DC2 Justin ALICH
"Carbon-14 and tritium radiolabeling of protein derivatives"
Justin Alich, Rafael Jiménez Rioboo, Grégory Pieters, Davide Audisio
In: Isotopically Labeled Compounds – Recent Advances and Emerging Topics in Synthesis and Applications
Elsevier, 2026, Pages 37–67